NBI 27914 hydrochloride
Catalog # 1591 | Tocris Bioscience a Bio-Techne Brand
Selective non-peptide CRF1 antagonist
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Key Product Details
Description: | Selective non-peptide CRF1 antagonist |
Chemical Name: | 5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine hydrochloride |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 470.66 |
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Citations for NBI 27914 hydrochloride (12)
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Citations are publications that use Bio-Techne products. Selected citations for NBI 27914 hydrochloride include:
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Navarro et al.
(2015)
Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine.
Stroke.
35:6639
PMID: 25926444 -
Rajbhandari et al.
(2015)
Predator Stress-Induced CRF Release Causes Enduring Sensitization of Basolateral Amygdala NE Systems that Promote PTSD-Like Startle Abnormalities.
J Neurosci.
35:14270
PMID: 26490866 -
Ji et al.
(2013)
Non-pain-related CRF1 activation in the amygdala facilitates synaptic transmission and pain responses.
Mol Pain.
9:2
PMID: 23410057 -
Jia et al.
(2013)
Role of nesfatin-1 in a rat model of visceral hypersensitivity.
Cereb Cortex.
19:3487
PMID: 23801843 -
Silberman and Winder
(2013)
Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala.
Neuropharmacology.
70:316
PMID: 23470280 -
Lowery-Gionta et al.
(2012)
Corticotropin releasing factor signaling in the central amygdala is recruited during binge-like ethanol consumption in C57BL/6J mice.
J Neurosci.
32:3405
PMID: 22399763 -
Wang et al.
(2011)
CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice.
PLoS One.
6:e16377
PMID: 21359208 -
Liu et al.
(2010)
Differential actions of urocortins on neurons of the myenteric division of the enteric nervous system in guinea pig distal colon.
Br J Pharmacol.
159:222
PMID: 20002096 -
Delawary et al.
(2010)
NMDAR2B tyrosine phosphorylation regulates anxiety-like behavior and CRF expression in the amygdala.
Mol Brain.
3:37
PMID: 21118530 -
Nakamura and Sapru
(2009)
Cardiovascular responses to microinjections of urocortins into the NTS: role of inotropic glutamate receptors.
Am J Physiol Heart Circ Physiol.
296:H2022
PMID: 19395554 -
Gutknecht et al.
(2008)
Expression, binding, and signaling properties of CRF2(a) receptors endogenously expressed in human retinoblastoma Y79 cells: passage-dependent regulation of functional receptors.
J Neurochem.
104:926
PMID: 17976162 -
Gallopin et al.
(2006)
Cortical sources of CRF, NKB, and CCK and their effects on pyramidal cells in the neocortex.
J Neurosci.
16:1440
PMID: 16339088
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