N20C hydrochloride

Name: N20C hydrochloride
Brand: Tocris Bioscience
SKU: 2213

Tocris Bioscience, part of Bio-Techne | Catalog # 2213

Citations (22)

COA / SDS

Non-competitive NMDA open-channel blocker

Discontinued Product

2213 has been discontinued. View all Additional NMDA Receptor Compounds products.

Key Product Details

Description:	Non-competitive NMDA open-channel blocker
Chemical Name:	2-[(3,3-Diphenylpropyl)amino]acetamide hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	304.82

View Full Technical Details for N20C hydrochloride

Technical Data
Citations

Biological Activity for N20C hydrochloride

Selective, non-competitive NMDA receptor antagonist (IC₅₀ = 5 μM); binds to the receptor-associated ion channel and prevents glutamate-induced Ca²⁺ influx. Displays neuroprotective activity in vivo. Brain-penetrant.

Technical Data for N20C hydrochloride

M. Wt	304.82
Formula	C₁₇H₂₀N₂O.HCl
Storage	Desiccate at +4°C
Purity	≥98% (HPLC)
CAS Number	1177583-87-7
PubChem ID	16759164
InChi Key	JCJDLPUASJEVRN-UHFFFAOYSA-N
Smiles	Cl.NC(=O)CNCCC(C1=CC=CC=C1)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for N20C hydrochloride

References are publications that support the biological activity of the product.

Planells-Cases A novel N-MthD.-aspartate receptor open channel blocker with in vivo neuroprotectant activity. J.Pharmacol.Exp.Ther. 2002 PMID: 12065713

N20C hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2213

Key Product Details

Biological Activity for N20C hydrochloride

Technical Data for N20C hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for N20C hydrochloride

Product Documents for N20C hydrochloride

COA

Certificate of Analysis

SDS

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