N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu
Tocris Bioscience, part of Bio-Techne | Catalog # 1927
Phosphopeptide ligand for src SH2 domain
Discontinued Product
1927 has been discontinued.
View all Src Family Kinase Ligands products.
Key Product Details
Description
Phosphopeptide ligand for src SH2 domain
Product Description
N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu is a phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.Product Specifications
Molecular Weight
803.71
Formula
C32H46N5O17P
Storage
Desiccate at -20°C
Chemical Name
N-Acetyl-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl]-L-α-glutamyl-L-isoleucyl]-L-glutamic acid
CAS Number
159439-02-8
PubChem ID
42628614
InChI Key
QQEKQSBIEKQXQS-PSCZMIBCSA-N
SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC1=CC=C(OP(O)(O)=O)C=C1)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Pacofsky Potent dipeptide inhibitors of the pp60c-src SH2 domain. J.Med.Chem. 1998 PMID: 9599239
- Park Design and characterization of non-phosphopeptide inhibitors for src family SH2 domains. Bioorg.Med.Chem.Lett. 2002 PMID: 12217360
- Gilmer Peptide inhibitors of src SH3-SH2-phosphoprotein interactions. J.Biol.Chem. 1994 PMID: 7527393
Product Specific Notices for N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu
For research use only
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