ML 402

Name: ML 402
Brand: Tocris Bioscience
SKU: 6888

Tocris Bioscience, part of Bio-Techne | Catalog # 6888

Citations (2)

COA / SDS

Selective TREK channel activator

Discontinued Product

6888 has been discontinued. View all Two-P Potassium Channels Activators products.

Key Product Details

Description:	Selective TREK channel activator
Chemical Name:	N-[2-(4-Chloro-2-methylphenoxy)ethyl]-2-thiophenecarboxamide
Purity:	≥98% (HPLC)
Molecular Weight:	295.78

View Full Technical Details for ML 402

Technical Data
Citations

Biological Activity for ML 402

ML 402 is a selective TREK channel activator. Selectively activates K_2P2.1 (TREK-1) and K_2P10.1 (TREK-2) with no significant effect at K_2P4.1 channels (TRAAK).

Compound Libraries for ML 402

ML 402 is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for ML 402

M. Wt	295.78
Formula	C₁₄H₁₄ClNO₂S
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	298684-44-3
PubChem ID	592973
InChi Key	RULQUKFOBAPKKR-UHFFFAOYSA-N
Smiles	CC1=C(OCCNC(=O)C2=CC=CS2)C=CC(Cl)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for ML 402

References are publications that support the biological activity of the product.

Lolicato K_2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site. Nature 2017 PMID: 28693035