ML 348

Tocris Bioscience, part of Bio-Techne | Catalog # 5345

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor
Discontinued Product
5345 has been discontinued. View all Hydrolase Inhibitors products.

Key Product Details

Description

Selective and reversible lysophospholipase 1 (LYPLA1) inhibitor

View all Hydrolase Inhibitors »

Product Description

ML 348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM). Exhibits 14-fold selectivity for LYPLA1 over LYPLA2. Also selective over a panel of ~30 other serine hydrolases.

Product Specifications

Molecular Weight

415.79

Formula

C18H17ClF3N3O3

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

N-[2-Chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide

CAS Number

899713-86-1

PubChem ID

3238952

InChI Key

OXKNHBBDOIMFFQ-UHFFFAOYSA-N

SMILES

ClC1=C(NC(CN2CCN(C(C3=CC=CO3)=O)CC2)=O)C=C(C(F)(F)F)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.58 100

Preparing Stock Solutions for ML 348

The following data is based on the product molecular weight 415.79

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.41 mL 12.03 mL 24.05 mL
5 mM 0.48 mL 2.41 mL 4.81 mL
10 mM 0.24 mL 1.20 mL 2.41 mL
50 mM 0.05 mL 0.24 mL 0.48 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for ML 348

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ML 348

For research use only

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