(-)-Cytisine
Tocris Bioscience, part of Bio-Techne | Catalog # 1390
Potent and selective neuronal nAChRagonist
Key Product Details
Description
Potent and selective neuronal nAChRagonist
Product Description
(-)-Cytisine is a potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors.Product Specifications
Molecular Weight
190.24
Formula
C11H14N2O
Storage
Desiccate at RT
Purity
≥99% (HPLC)
Chemical Name
(1R,5S)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one
CAS Number
485-35-8
PubChem ID
10235
InChI Key
ANJTVLIZGCUXLD-DTWKUNHWSA-N
SMILES
O=C2N1C[C@@]([H])(C3)CNC[C@@]([H])3C1=CC=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 100 |
Preparing Stock Solutions
for (-)-Cytisine
The following data is based on the product molecular weight 190.24
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.26 mL | 26.28 mL | 52.57 mL |
| 5 mM | 1.05 mL | 5.26 mL | 10.51 mL |
| 10 mM | 0.53 mL | 2.63 mL | 5.26 mL |
| 50 mM | 0.11 mL | 0.53 mL | 1.05 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Papke Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit. Mol.Pharmacol. 1994 PMID: 8302273
- Reavill Behavioural and pharmacokinetic studies on nicotine, cytisine and lobeline. Neuropharmacology 1990 PMID: 2385332
- Happe Localization of nicotinic cholinergic receptors in rat brain: autoradiographic studies with [3H]cytisine. Neuroscience 1994 PMID: 7870314
Product Specific Notices for (-)-Cytisine
For research use only
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