Midazolam hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 2832
Benzodiazepine agonist
Discontinued Product
2832 has been discontinued.
View all GABA-A Receptor Benzodiazepines products.
Key Product Details
Description
Benzodiazepine agonist
Alternative Names
Dormicum,Ro 21-3981/001
Product Description
Midazolam hydrochloride is a sedative/hypnotic agent that acts at the GABAA receptor benzodiazepine modulatory site.Product Specifications
Molecular Weight
362.23
Formula
C18H13ClFN3.HCl
Storage
Desiccate at RT
Purity
≥99% (HPLC)
Chemical Name
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine hydrochloride
CAS Number
59467-96-8
PubChem ID
43032
InChI Key
PLYSCVSCYOQVRP-UHFFFAOYSA-N
SMILES
FC(C=CC=C4)=C4C3=NCC1=CN=C(C)N1C2=CC=C(Cl)C=C23.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 9.06 | 25 |
Preparing Stock Solutions
for Midazolam hydrochloride
The following data is based on the product molecular weight 362.23
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 11.04 mL | 55.21 mL | 110.43 mL |
| 1.25 mM | 2.21 mL | 11.04 mL | 22.09 mL |
| 2.5 mM | 1.10 mL | 5.52 mL | 11.04 mL |
| 12.5 mM | 0.22 mL | 1.10 mL | 2.21 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Olkkola and Ahonen Midazolam and other benzodiazepines. Handb.Exp.Pharmacol. 2008 PMID: 18175099
- Kanto Midazolam: the first water-soluble benzodiazepine. Pharmacology, pharmacokinetics and efficacy in insomnia and anesthesia. Pharmacotherapy 1985 PMID: 3161005
Product Specific Notices for Midazolam hydrochloride
For research use only
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