MAP4

Name: MAP4
Brand: Tocris Bioscience
SKU: 0711

Tocris Bioscience, part of Bio-Techne | Catalog # 0711

Citations (1)

COA / SDS

Potent group II mGlu agonist; also group III mGlu antagonist

Discontinued Product

0711 has been discontinued. View all Group II mGluR Agonists products.

Key Product Details

Description:	Potent group II mGlu agonist; also group III mGlu antagonist
Chemical Name:	(S)-2-Amino-2-methyl-4-phosphonobutanoic acid
Purity:	≥96% (HPLC)
Molecular Weight:	197.13

View Full Technical Details for MAP4

Technical Data
Citations

Biological Activity for MAP4

MAP4 is a selective group III metabotropic glutamate receptor antagonist in some electrophysiological systems. Group II/group III agonist in certain neurochemical systems.

Technical Data for MAP4

M. Wt	197.13
Formula	C₅H₁₂NO₅P
Storage	Store at RT
Purity	≥96% (HPLC)
CAS Number	157381-42-5
PubChem ID	1795545
InChi Key	HONKEGXLWUDTCF-YFKPBYRVSA-N
Smiles	N[C@](CCP(O)(O)=O)(C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for MAP4

References are publications that support the biological activity of the product.

Sekiyama Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 1996 PMID: 8730745
Kemp Agonists of cyclic AMP-coupled metabotropic glutamate receptors in adult rat cortical slices. Eur.J.Pharmacol. 1996 PMID: 8864697
Salt and Eaton Distinct presynaptic metabotropic receptors for L-AP4 and CCGl on GABAergic terminals: pharmacological evidence using novel α-methyl derivative mGluR antagonists, MAP4 and MCCG, in the rat thalamus in vivo. Neuroscience 1995 PMID: 7753406
Jane Actions of two new sub-type selective metabotropic glutamate receptor antagonists in the neonatal rat spinal cord. Br.J.Pharmacol. 1994 PMID: 7921606

MAP4

Tocris Bioscience, part of Bio-Techne | Catalog # 0711

Key Product Details

Biological Activity for MAP4

Technical Data for MAP4

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for MAP4

Product Documents for MAP4

COA

Certificate of Analysis

SDS

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