m-3M3FBS
Tocris Bioscience, part of Bio-Techne | Catalog # 1941
Phospholipase C activator
Product Description
m-3M3FBS is an activator of phospholipase C (PLC). Stimulates superoxide generation, Ca2+ release and inositol phosphate formation in a variety of cell types. Also inhibits growth of the leukemic cell lines U937 and THP-1.Negative Control also available.
Product Specifications
Molecular Weight
343.36
Formula
C16H16F3NO2S
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
2,4,6-Trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
CAS Number
200933-14-8
PubChem ID
761523
InChI Key
ZIIUUSVHCHPIQD-UHFFFAOYSA-N
SMILES
CC1=CC(C)=C(C(C)=C1)S(=O)(=O)NC1=CC=CC(=C1)C(F)(F)F
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.34 | 100 | |
| Ethanol | 34.34 | 100 |
Preparing Stock Solutions
for m-3M3FBS
The following data is based on the product molecular weight 343.36
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.91 mL | 14.56 mL | 29.12 mL |
| 5 mM | 0.58 mL | 2.91 mL | 5.82 mL |
| 10 mM | 0.29 mL | 1.46 mL | 2.91 mL |
| 50 mM | 0.06 mL | 0.29 mL | 0.58 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Krjukova Phospholipase C activator m-3M3FBS affects Ca2+ homeostasis independently of phospholipase C activation. Br.J.Pharmacol. 2004 PMID: 15302681
- Lee The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis. Cancer Lett. 2005 PMID: 15863272
- Bae Identification of a compound that directly stimulates phospholipase C activity. Mol.Pharmacol. 2003 PMID: 12695532
Product Specific Notices for m-3M3FBS
For research use only
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