LY 310762 hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 3078
Selective 5-HT1D antagonist
Product Description
LY 310762 hydrochloride is a 5-HT1D-preferring receptor antagonist (EC50 = 31 nM). Displays no activity on 5-HT transport.Licensing Information
Sold under license from Eli Lilly and companyProduct Specifications
Molecular Weight
430.94
Formula
C24H27FN2O2.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride
CAS Number
192927-92-7
PubChem ID
11957576
InChI Key
BOCLFQZPFYNVFD-UHFFFAOYSA-N
SMILES
CC(C1=CC=CC=C1N2CCN3CCC(C(C4=CC=C(F)C=C4)=O)CC3)(C)C2=O.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 4.31 | 10 | |
| DMSO | 43.09 | 100 |
Preparing Stock Solutions
for LY 310762 hydrochloride
The following data is based on the product molecular weight 430.94
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.32 mL | 11.60 mL | 23.21 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
| 10 mM | 0.23 mL | 1.16 mL | 2.32 mL |
| 50 mM | 0.05 mL | 0.23 mL | 0.46 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Pullar The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. Eur.J.Pharmacol. 2004 PMID: 15189767
Product Specific Notices for LY 310762 hydrochloride
For research use only
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