Losartan potassium

Tocris Bioscience, part of Bio-Techne | Catalog # 3798

Selective, non-peptide AT1 antagonist
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Key Product Details

Description

Selective, non-peptide AT1 antagonist

Alternative Names

DuP-753

View all Angiotensin AT1 Receptor Antagonists »

Product Description

Losartan potassium is a selective non-peptide angiotensin AT1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA2 = 8.27). Orally active antihypertensive agent. Attenuates lung damage in a mouse model of SARS-CoV infection.

Product Specifications

Molecular Weight

461.00

Formula

C22H22ClKN6O

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol potassium salt

CAS Number

124750-99-8

PubChem ID

11476710

InChI Key

OXCMYAYHXIHQOA-UHFFFAOYSA-N

SMILES

CCCCC1=NC(Cl)=C(CO)N1CC2=CC=C(C3=CC=CC=C3C(N=N4)=NN4[K])C=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 46.1 100
DMSO 46.1 100

Preparing Stock Solutions for Losartan potassium

The following data is based on the product molecular weight 461.00

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.17 mL 10.85 mL 21.69 mL
5 mM 0.43 mL 2.17 mL 4.34 mL
10 mM 0.22 mL 1.08 mL 2.17 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

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Product Documents for Losartan potassium

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Losartan potassium

For research use only

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