Lidocaine
Tocris Bioscience, part of Bio-Techne | Catalog # 3057
Na+ channel blocker
Key Product Details
Description
Na+ channel blocker
Product Description
Lidocaine is an anasthetic and class Ib antiarrhythmic agent. Blocks voltage-gated sodium channels in the inactivated state.Product Specifications
Molecular Weight
234.34
Formula
C14H22N2O
Storage
Store at RT
Purity
≥98% (HPLC)
Chemical Name
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
CAS Number
137-58-6
PubChem ID
3676
InChI Key
NNJVILVZKWQKPM-UHFFFAOYSA-N
SMILES
O=C(CN(CC)CC)NC1=C(C)C=CC=C1C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 23.43 | 100 | |
| Ethanol | 23.43 | 100 |
Preparing Stock Solutions
for Lidocaine
The following data is based on the product molecular weight 234.34
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.27 mL | 21.34 mL | 42.67 mL |
| 5 mM | 0.85 mL | 4.27 mL | 8.53 mL |
| 10 mM | 0.43 mL | 2.13 mL | 4.27 mL |
| 50 mM | 0.09 mL | 0.43 mL | 0.85 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Sarraf Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats. Br.J.Pharmacol. 2003 PMID: 12922925
Product Specific Notices for Lidocaine
For research use only
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