Leuprolide

Name: Leuprolide
Brand: Tocris Bioscience
SKU: 2873

Tocris Bioscience, part of Bio-Techne | Catalog # 2873

COA / SDS

GnRH receptor agonist

Discontinued Product

2873 has been discontinued. View all GnRH Agonist products.

Key Product Details

Description:	GnRH receptor agonist
Alternative Names:	Leuoprorelin
Molecular Weight:	1209.41

View Full Technical Details for Leuprolide

Technical Data
Citations

Biological Activity for Leuprolide

Leuprolide is a gonadotropin-releasing hormone (GnRH, luteinizing hormone-releasing hormone, LHRH) receptor agonist. Suppresses estradiol, LH and FSH serum levels and represses the growth of experimental rat endometriosis.

Technical Data for Leuprolide

M. Wt	1209.41
Formula	C₅₉H₈₄N₁₆O₁₂
Single Letter Sequence	XHWSYLLRP (Modifications: X1 = Glp, Pro-9 = Pro-NHEt)
Storage	Desiccate at -20°C
CAS Number	53714-56-0
PubChem ID	90488782
InChi Key	GFIJNRVAKGFPGQ-UILVTTEASA-N
Smiles	[H]N1[C@@H](CCC1=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Leuprolide

References are publications that support the biological activity of the product.

Uday LHRH antagonist attenuates the effect of fluox. on marble-burying behavior in mice. Eur.J.Pharmacol. 2007 PMID: 17368614
Salvador Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leupr. on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. Eur.J.Pharmacol.
Okada One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J.Pharmacol.Exp.Ther. 1988 PMID: 3126294

Leuprolide

Tocris Bioscience, part of Bio-Techne | Catalog # 2873

Key Product Details

Biological Activity for Leuprolide

Technical Data for Leuprolide

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Leuprolide

Product Documents for Leuprolide

COA

Certificate of Analysis

SDS

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