Leupeptin hemisulfate

Name: Leupeptin hemisulfate
Brand: Tocris Bioscience
SKU: 1167
Rating: 4 (2 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 1167

(2)

Citations (29)

COA / SDS

Inhibits trypsin-like/cysteine proteases

Key Product Details

Description:	Inhibits trypsin-like/cysteine proteases
Purity:	≥95% (HPLC)
Molecular Weight:	475.6

View Full Technical Details for Leupeptin hemisulfate

Technical Data
Citations / Reviews (2)

Biological Activity for Leupeptin hemisulfate

Leupeptin hemisulfate is a reversible inhibitor of trypsin-like and cysteine proteases such as calpain. Shown to inhibit activation-induced programmed cell death.

Technical Data for Leupeptin hemisulfate

M. Wt	475.6
Formula	C₂₀H₃₈N₆O₄.½H₂SO₄
Single Letter Sequence	LLR (Modifications: Leu-1 = N-terminal Ac, Arg-3 = Arginal)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	103476-89-7
PubChem ID	2733491
InChi Key	CIPMKIHUGVGQTG-VFFZMTJFSA-N
Smiles	OS(O)(=O)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Leupeptin hemisulfate

Solubility

Soluble to 10mg/ml in water

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References for Leupeptin hemisulfate

References are publications that support the biological activity of the product.

Sarin Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors. J.Immunol. 1994 PMID: 8021517
Wang Developing selective inhibitors of calpain. TiPS 1990 PMID: 2185586
Mehdi Cell-penetrating inhibitors of calpain. TiBS 1991 PMID: 1877091