LEP (116-130) (mouse)

Name: LEP (116-130) (mouse)
Brand: Tocris Bioscience
SKU: 2985

Tocris Bioscience, part of Bio-Techne | Catalog # 2985

COA / SDS

Synthetic leptin peptide fragment

Discontinued Product

2985 has been discontinued. View all Leptin Receptor Peptides products.

Key Product Details

Description:	Synthetic leptin peptide fragment
Molecular Weight:	1560.73

View Full Technical Details for LEP (116-130) (mouse)

Technical Data
Citations

Biological Activity for LEP (116-130) (mouse)

LEP (116-130) (mouse) is a synthetic leptin peptide fragment. Restricts weight gain and reduces food intake in female mice lacking endogenously circulating active leptin.

Technical Data for LEP (116-130) (mouse)

M. Wt	1560.73
Formula	C₆₄H₁₀₉N₁₉O₂₄S
Single Letter Sequence	SCSLPQTSGLQKPES (Modifications: Ser-15 = C-terminal amide)
Storage	Desiccate at -20°C
CAS Number	258276-95-8
PubChem ID	90471193
InChi Key	YEHDWBRMEXDYLT-RDEOYNLOSA-N
Smiles	[H]N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for LEP (116-130) (mouse)

References are publications that support the biological activity of the product.

Grasso Inhibitory effects of leptin-related synthetic peptide 116-130 on food intake and body weight gain in female C57BL/6J ob/ob mice may not be mediated by peptide activation of the long isoform of the leptin receptor. Diabetes 1999 PMID: 10535455
Rozhavskaya Design of a synthetic leptin agonist: effects on energy balance, glucose homeostasis and thermoregulation. Endocrinology 2000 PMID: 10875251
Grasso In vivo effects of leptin-related synthetic peptides on body weight and food intake in female ob/ob mice: localization of leptin activity to domains between amino acid residues 106-140. Endocrinology 1997 PMID: 9075696

LEP (116-130) (mouse)

Tocris Bioscience, part of Bio-Techne | Catalog # 2985

Key Product Details

Biological Activity for LEP (116-130) (mouse)

Technical Data for LEP (116-130) (mouse)

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for LEP (116-130) (mouse)

Product Documents for LEP (116-130) (mouse)

COA

Certificate of Analysis

SDS

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