LDN 27219

Tocris Bioscience, part of Bio-Techne | Catalog # 4602

Transglutaminase 2 (TG2) inhibitor; reversible
Discontinued Product
4602 has been discontinued. View all Additional Transferase Products products.

Key Product Details

Description

Transglutaminase 2 (TG2) inhibitor; reversible

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Product Description

LDN 27219 is a transglutaminase 2 (TG2) inhibitor (IC50 = 0.25 μM). Binds at GTPase site; reversible.

Product Specifications

Molecular Weight

408.50

Formula

C20H16N4O2S2

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

2-[(3,4-Dihydro-4-oxo-3,5-diphenylthieno[2,3-d]pyrimidin-2-yl)thio]acetic acid hydrazide

CAS Number

312946-37-5

PubChem ID

1150683

InChI Key

WLBUICQBNZXIDJ-UHFFFAOYSA-N

SMILES

O=C(NN)CSC(N1C2=CC=CC=C2)=NC3=C(C(C4=CC=CC=C4)=CS3)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.85 100

Preparing Stock Solutions for LDN 27219

The following data is based on the product molecular weight 408.50

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.45 mL 12.24 mL 24.48 mL
5 mM 0.49 mL 2.45 mL 4.90 mL
10 mM 0.24 mL 1.22 mL 2.45 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

Molarity Calculator

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for LDN 27219

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for LDN 27219

For research use only

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