Lazabemide hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 2460

Selective MAO-B inhibitor
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Key Product Details

Description

Selective MAO-B inhibitor

Alternative Names

Ro 19-6327

View all Monoamine Oxidase (MAO) Inhibitors »

Product Description

Lazabemide hydrochloride is a selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). Inhibits monoamine uptake at high concentrations (IC50 values are 86, 123 and > 500 μM for noradrenalin, serotonin and dopamine uptake respectively).

Product Specifications

Molecular Weight

236.10

Formula

C8H10ClN3O.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride

CAS Number

103878-83-7

PubChem ID

163727

InChI Key

JMFKTFLARGGXCC-UHFFFAOYSA-N

SMILES

Cl.NCCNC(=O)C1=NC=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 23.61 100
DMSO 23.61 100

Preparing Stock Solutions for Lazabemide hydrochloride

The following data is based on the product molecular weight 236.10

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.24 mL 21.18 mL 42.35 mL
5 mM 0.85 mL 4.24 mL 8.47 mL
10 mM 0.42 mL 2.12 mL 4.24 mL
50 mM 0.08 mL 0.42 mL 0.85 mL

Calculators

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Reconstitution Calculator

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Product Documents for Lazabemide hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Lazabemide hydrochloride

For research use only

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