Lamotrigine

Tocris Bioscience, part of Bio-Techne | Catalog # 1611

Inhibits glutamate release. Anticonvulsant
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Key Product Details

Description

Inhibits glutamate release. Anticonvulsant

View all Glutamate Receptor Compounds »

Product Description

Lamotrigine is an anticonvulsant. Inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents. Also blocks heterologously expressed and native α4β2 nAChRs with a similar affinity to Na+ channels.

Water-soluble Salt also available.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Product Specifications

Molecular Weight

256.09

Formula

C9H7Cl2N5

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine

CAS Number

84057-84-1

PubChem ID

3878

InChI Key

PYZRQGJRPPTADH-UHFFFAOYSA-N

SMILES

NC1=NC(N)=C(N=N1)C1=CC=CC(Cl)=C1Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 25.61 100

Preparing Stock Solutions for Lamotrigine

The following data is based on the product molecular weight 256.09

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.90 mL 19.52 mL 39.05 mL
5 mM 0.78 mL 3.90 mL 7.81 mL
10 mM 0.39 mL 1.95 mL 3.90 mL
50 mM 0.08 mL 0.39 mL 0.78 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Lamotrigine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Lamotrigine

For research use only

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