L-NAME hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0665
Non-selective NOS inhibitor
Product Description
L-NAME hydrochloride is a NO synthase inhibitor.Product Specifications
Molecular Weight
269.69
Formula
C7H15N5O4.HCl
Storage
Store at RT
Chemical Name
NG-Nitro-L-arginine methyl ester hydrochloride
CAS Number
51298-62-5
PubChem ID
135193
InChI Key
QBNXAGZYLSRPJK-JEDNCBNOSA-N
SMILES
N=C(NCCC[C@H](N)C(OC)=O)N[N+]([O-])=O.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 26.97 | 100 | |
| DMSO | 26.97 | 100 |
Preparing Stock Solutions
for L-NAME hydrochloride
The following data is based on the product molecular weight 269.69
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.71 mL | 18.54 mL | 37.08 mL |
| 5 mM | 0.74 mL | 3.71 mL | 7.42 mL |
| 10 mM | 0.37 mL | 1.85 mL | 3.71 mL |
| 50 mM | 0.07 mL | 0.37 mL | 0.74 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Moore and Handy Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 1997 PMID: 9226999
- Pfeiffer Inhibition of nitric oxide synthesis by NG-nitro-L-arginine methyl ester (L-NAME): requirement for bioactivation to the free acid, NG-nitro-L-arginine. Br.J.Pharmacol. 1996 PMID: 8832069
- Knowles Nitric oxide synthases in mammals. Biochem.J. 1994 PMID: 7510950
Product Specific Notices for L-NAME hydrochloride
For research use only
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