KN 92
Tocris Bioscience, part of Bio-Techne | Catalog # 4130
Inactive analog of KN 93. K+ channel (Kv) blocker
Key Product Details
Description
Inactive analog of KN 93. K+ channel (Kv) blocker
Product Description
KN 92 is an inactive analog of the CaM kinase II inhibitor KN 93 . Potassium channel (Kv1.2, 1.4, 1.5, 2.1, 3.2 and hERG) blocker in vitro.Active Analog also available.
Product Specifications
Molecular Weight
554.98
Formula
C24H25ClN2O3S.H3PO4
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
2-[N-(4'-Methoxybenzenesulfonyl)]amino-N-(4'-chlorophenyl)-2-propenyl-N-methylbenzylamine phosphate
CAS Number
1135280-28-2
PubChem ID
16219540
InChI Key
XRQHWVVDNMJDEQ-IPZCTEOASA-N
SMILES
ClC1=CC=C(/C=C/CN(C)CC2=CC=CC=C2NS(=O)(C3=CC=C(OC)C=C3)=O)C=C1.OP(O)(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 5.55 | 10 |
Preparing Stock Solutions
for KN 92
The following data is based on the product molecular weight 554.98
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.02 mL | 90.09 mL | 180.19 mL |
| 0.5 mM | 3.60 mL | 18.02 mL | 36.04 mL |
| 1 mM | 1.80 mL | 9.01 mL | 18.02 mL |
| 5 mM | 0.36 mL | 1.80 mL | 3.60 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for KN 92
For research use only
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