KF 38789

Tocris Bioscience, part of Bio-Techne | Catalog # 2748

Selective inhibitor of P-selectin-mediated cell adhesion
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Key Product Details

Description

Selective inhibitor of P-selectin-mediated cell adhesion

View all Cell Adhesion Inhibitors »

Product Description

KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion (IC50 = 1.97 μM) that displays no effects on L-selectin- and E-selectin-mediated adhesion. KF 38789 blocks P-selectin-mediated binding in vitro and leukocyte accumulation in vivo.

Product Specifications

Molecular Weight

375.44

Formula

C19H21NO5S

Storage

Desiccate at +4°C

Purity

≥97% (HPLC)

Chemical Name

3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one

CAS Number

257292-29-8

PubChem ID

5373277

InChI Key

FJDFKOSFDPIMBV-NBVRZTHBSA-N

SMILES

COC1=CC=C(C2CC(=NCCS2)C2=C(O)C=C(C)OC2=O)C(OC)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 37.54 100

Preparing Stock Solutions for KF 38789

The following data is based on the product molecular weight 375.44

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.66 mL 13.32 mL 26.64 mL
5 mM 0.53 mL 2.66 mL 5.33 mL
10 mM 0.27 mL 1.33 mL 2.66 mL
50 mM 0.05 mL 0.27 mL 0.53 mL

Calculators

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Product Documents for KF 38789

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for KF 38789

For research use only

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