KB-R7943 mesylate

Tocris Bioscience, part of Bio-Techne | Catalog # 1244

Na+/Ca2+ exchange inhibitor (reverse mode)
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Key Product Details

Description

Na+/Ca2+ exchange inhibitor (reverse mode)

View all Na+/Ca2+ Exchanger Inhibitors »

Product Description

KB-R7943 mesylate is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). Also inhibits the mitochondrial Ca2+ uniporter (MCU; IC50 = 5.5 μM). Does not affect Na+-dependent transport systems or ionotropic glutamate receptors.

Product Specifications

Molecular Weight

427.49

Formula

C16H17N3O3S.CH3SO3H

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-[2-[4-(4-Nitrobenzyloxy)phenyl]ethyl]isothiourea mesylate

CAS Number

182004-65-5

PubChem ID

9823846

InChI Key

WGIKEBHIKKWJLG-UHFFFAOYSA-N

SMILES

CS(O)(=O)=O.NC(=N)SCCC1=CC=C(OCC2=CC=C(C=C2)[N+]([O-])=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.75 100

Preparing Stock Solutions for KB-R7943 mesylate

The following data is based on the product molecular weight 427.49

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.34 mL 11.70 mL 23.39 mL
5 mM 0.47 mL 2.34 mL 4.68 mL
10 mM 0.23 mL 1.17 mL 2.34 mL
50 mM 0.05 mL 0.23 mL 0.47 mL

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Product Documents for KB-R7943 mesylate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for KB-R7943 mesylate

For research use only

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