JPS016NC

Name: JPS016NC
Brand: Tocris Bioscience
SKU: 8084

Tocris Bioscience, part of Bio-Techne | Catalog # 8084

COA / SDS

Negative control for JPS036 (Cat. No. 8085).

Key Product Details

Description:	Negative control for JPS036 (Cat. No. 8085).
Chemical Name:	(2S,4S)-1-((S)-2-(2-((9-(2-((4-((2-Aminophenyl)carbamoyl)phenyl)amino)-2-oxoethoxy)nonyl)oxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity:	≥97% (HPLC)
Molecular Weight:	898.13

View Full Technical Details for JPS016NC

Technical Data
Citations

Biological Activity for JPS016NC

JPS016NC is the negative control for JPS036 (Cat. No. 8085).

Licensing Information

Sold under license from the University of Leicester

Technical Data for JPS016NC

M. Wt	898.13
Formula	C₄₈H₆₃N₇O₈S
Storage	Store at -20°C
Purity	≥97% (HPLC)
CAS Number	3031358-94-5
InChi Key	BOXZMOCGSKLDAH-REIIXUMVSA-N
Smiles	NC(C=CC=C1)=C1NC(C(C=C2)=CC=C2NC(COCCCCCCCCCOCC(N[C@@H](C(C)(C)C)C(N3[C@@H](C[C@@H](C3)O)C(NCC4=CC=C(C5=C(C)N=CS5)C=C4)=O)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for JPS016NC

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	89.81	100

Preparing Stock Solutions for JPS016NC

The following data is based on the product molecular weight 898.13.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.11 mL	5.57 mL	11.13 mL
5 mM	0.22 mL	1.11 mL	2.23 mL
10 mM	0.11 mL	0.56 mL	1.11 mL
50 mM	0.02 mL	0.11 mL	0.22 mL

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Reconstitution Calculator

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References for JPS016NC

References are publications that support the biological activity of the product.

Smalley Optimization of class I histone deacetylase PROTACs reveals that HDAC1/2 degradation is critical to induce apoptosis and cell arrest in cancer cells. J.Med.Chem. 2022 PMID: 35293758