Isamoltane hemifumarate
Tocris Bioscience, part of Bio-Techne | Catalog # 0992
5-HT1B antagonist
Discontinued Product
0992 has been discontinued.
View all 5-HT1B Receptor Antagonists products.
Product Description
Isamoltane hemifumarate is a 5-HT1B antagonist, approximately 30-fold selective over 5-HT1A. Also possesses affinity for β-adrenergic receptors.Product Specifications
Molecular Weight
332.40
Formula
C16H22N2O2.½C4H4O4
Storage
Desiccate at +4°C
Purity
≥99% (HPLC)
Chemical Name
1-[(1-Methylethyl)amino]-3-[2-(1H-pyrrol-1-yl)]-propan-2-ol hemifumarate
CAS Number
874882-92-5
PubChem ID
45073435
InChI Key
MCHSBYUSDSJLAQ-WXXKFALUSA-N
SMILES
[H]OC(=O)\C=C\C(=O)O[H].CC(C)NCC(O)COC1=CC=CC=C1N1C=CC=C1.CC(C)NCC(O)COC1=CC=CC=C1N1C=CC=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 3.32 | 10 with gentle warming |
Preparing Stock Solutions
for Isamoltane hemifumarate
The following data is based on the product molecular weight 332.40
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.08 mL | 150.42 mL | 300.84 mL |
| 0.5 mM | 6.02 mL | 30.08 mL | 60.17 mL |
| 1 mM | 3.01 mL | 15.04 mL | 30.08 mL |
| 5 mM | 0.60 mL | 3.01 mL | 6.02 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Waldmeier Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain. Naunyn Schmiedebergs Arch.Pharmacol. 1988 PMID: 2905765
Product Specific Notices for Isamoltane hemifumarate
For research use only
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