iP300v
Tocris Bioscience, part of Bio-Techne | Catalog # 7584
Negative control for iP300w (Cat. No. 7270)
Key Product Details
Description
Negative control for iP300w (Cat. No. 7270)
Product Description
iP300v is a negative control for iP300w (Cat. No. 7270)Product Specifications
Molecular Weight
618.55
Formula
C29H27F5N6O4
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
(1'R,3'S)-3'-Fluoro-N-[(4-fluorophenyl)methyl]-2',3'-dihydro-5'-[1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-2,5-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[imidazolidine-4,1'-[1H]indene]-1-acetamide
CAS Number
2763218-94-4
InChI Key
SWXCHCQCWFXILM-YRTQXHIJSA-N
SMILES
O=C(NC)CN(N=C1)C=C1C(C=C2)=CC3=C2[C@](N4)(C[C@@H]3F)C(N(CC(N(CC5=CC=C(F)C=C5)[C@@H](C)C(F)(F)F)=O)C4=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 61.85 | 100 |
Preparing Stock Solutions
for iP300v
The following data is based on the product molecular weight 618.55
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.62 mL | 8.08 mL | 16.17 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.23 mL |
| 10 mM | 0.16 mL | 0.81 mL | 1.62 mL |
| 50 mM | 0.03 mL | 0.16 mL | 0.32 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Bosnakovski Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma. Oncogenesis
- Bosnakovski A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death. Sci.Adv. 2019 PMID: 31535023
Product Specific Notices for iP300v
For research use only
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