Ionomycin free acid
Tocris Bioscience, part of Bio-Techne | Catalog # 2092
Calcium ionophore
Product Description
Ionomycin free acid is a calcium ionophore; more specific than A23187.Calcium Salt also available.
Product Specifications
Molecular Weight
709.01
Formula
C41H72O9
Storage
Store at -20°C
Purity
≥95% (HPLC)
Chemical Name
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid
CAS Number
56092-81-0
PubChem ID
6912226
InChI Key
PGHMRUGBZOYCAA-ADZNBVRBSA-N
SMILES
O=C(O)CC[C@@H](C)C[C@H](C)C[C@H](C)C(/C=C(O)/[C@H](C)C[C@@H](C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@]([C@]2([H])O[C@@]([C@H](O)C)(C)CC2)(C)O1)C)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 7.09 | 10 |
Preparing Stock Solutions
for Ionomycin free acid
The following data is based on the product molecular weight 709.01
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.10 mL | 70.52 mL | 141.04 mL |
| 0.5 mM | 2.82 mL | 14.10 mL | 28.21 mL |
| 1 mM | 1.41 mL | 7.05 mL | 14.10 mL |
| 5 mM | 0.28 mL | 1.41 mL | 2.82 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Kaufmann Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria. J.Biol.Chem. 1980 PMID: 6766939
- Elzi Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. Am.J.Physiol.Cell Physiol. 2001 PMID: 11401859
- Liu and Hermann Characterization of ionomycin as a calcium ionophore. J.Biol.Chem. 1978 PMID: 28319
Product Specific Notices for Ionomycin free acid
For research use only
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