Imiloxan hydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 0986
Highly selective α2B antagonist
Key Product Details
Description
Highly selective α2B antagonist
Alternative Names
RS 21361
Product Description
Imiloxan hydrochloride is a moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity.Licensing Information
Sold with the permission of Roche BioscienceProduct Specifications
Molecular Weight
280.75
Formula
C14H16N2O2.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxan hydrochloride
CAS Number
81167-22-8
PubChem ID
172975
InChI Key
ANDJPJNFVJXEKX-UHFFFAOYSA-N
SMILES
Cl.CCN1C=CN=C1CC1COC2=CC=CC=C2O1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 28.07 | 100 |
Preparing Stock Solutions
for Imiloxan hydrochloride
The following data is based on the product molecular weight 280.75
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.56 mL | 17.81 mL | 35.62 mL |
| 5 mM | 0.71 mL | 3.56 mL | 7.12 mL |
| 10 mM | 0.36 mL | 1.78 mL | 3.56 mL |
| 50 mM | 0.07 mL | 0.36 mL | 0.71 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Michel and Whiting 2-(2-Imidazolylmethyl)-1,4-benzodioxans, a series of selective alpha2-adrenoceptor antagonists. Br.J.Pharmacol.
- Michel Assessment of imiloxan as a selective α2B-adrenoceptor antagonist. Br.J.Pharmacol. 1990 PMID: 1970500
Product Specific Notices for Imiloxan hydrochloride
For research use only
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