Idebenone

Name: Idebenone
Brand: Tocris Bioscience
SKU: 3002

Tocris Bioscience, part of Bio-Techne | Catalog # 3002

Citations (11)

COA / SDS

Antioxidant and neuroprotective agent

Discontinued Product

3002 has been discontinued. View all Additional Antioxidant Compounds products.

Key Product Details

Description:	Antioxidant and neuroprotective agent
Chemical Name:	2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione
Purity:	≥99% (HPLC)
Molecular Weight:	338.44

View Full Technical Details for Idebenone

Technical Data
Citations

Biological Activity for Idebenone

Idebenone is an antioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid peroxidation and blocks glutamate neurotoxicity in vitro and in vivo. Inhibits apoptosis of astrocytes via increased NGF production.

Technical Data for Idebenone

M. Wt	338.44
Formula	C₁₉H₃₀O₅
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	58186-27-9
PubChem ID	3686
InChi Key	JGPMMRGNQUBGND-UHFFFAOYSA-N
Smiles	O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Idebenone

References are publications that support the biological activity of the product.

Civenni Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes. Eur.J.Pharmacol. 1999 PMID: 10323265
Takuma CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production. Eur.J.Pharmacol. 2000 PMID: 11040339
Zs-Nagy Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review. Arch.Gerontol.Geriatr. 1990 PMID: 15374467

Idebenone

Tocris Bioscience, part of Bio-Techne | Catalog # 3002

Key Product Details

Biological Activity for Idebenone

Technical Data for Idebenone

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Idebenone

Product Documents for Idebenone

COA

Certificate of Analysis

SDS

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