GW 542573X

Tocris Bioscience, part of Bio-Techne | Catalog # 4311

Selective KCa2.1 (SK) channel activator
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Key Product Details

Description

Selective KCa2.1 (SK) channel activator

View all Ca2+-Activated Potassium Channel Activators »

Product Description

GW 542573X is an activator of small-conductance Ca2+-activated K+ channels (KCa2); selective for KCa2.1 (EC50 = 8.2 μM in HEK293 cells expressing hKCa2.1) with the profile hKCa2.1 > hKCa2.2 = hKCa2.3 > hKCa3.1 (IK).

Product Specifications

Molecular Weight

364.44

Formula

C19H28N2O5

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

4-[[[[(2-Methoxyphenyl)amino]carbonyl]oxy]methyl]-piperidinecarboxylic acid-1,1-dimethylethyl ester

CAS Number

660846-41-3

PubChem ID

24885053

InChI Key

SAXGSDIZIYFNKD-UHFFFAOYSA-N

SMILES

O=C(OC(C)(C)C)N1CCC(COC(NC2=CC=CC=C2OC)=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.44 100
Ethanol 36.44 100

Preparing Stock Solutions for GW 542573X

The following data is based on the product molecular weight 364.44

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.74 mL 13.72 mL 27.44 mL
5 mM 0.55 mL 2.74 mL 5.49 mL
10 mM 0.27 mL 1.37 mL 2.74 mL
50 mM 0.05 mL 0.27 mL 0.55 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for GW 542573X

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GW 542573X

For research use only

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