GMQ hydrochloride

Name: GMQ hydrochloride
Brand: Tocris Bioscience
SKU: 5028

Tocris Bioscience, part of Bio-Techne | Catalog # 5028

COA / SDS

Selective ASIC3 opener

Discontinued Product

5028 has been discontinued. View all Ion Channel Modulators products.

Key Product Details

Description:	Selective ASIC3 opener
Chemical Name:	N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	237.69

View Full Technical Details for GMQ hydrochloride

Technical Data
Citations

Biological Activity for GMQ hydrochloride

GMQ hydrochloride is a selective opener of acid-sensing ion channel 3 (ASIC3) at pH 7.4. Alters the pH dependence of ASIC1a and ASIC1b; does not affect the activation curve of ASIC2a.

Technical Data for GMQ hydrochloride

M. Wt	237.69
Formula	C₁₀H₁₁N₅.HCl
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	5361-15-9
PubChem ID	12253739
InChi Key	VNPZWQRWOHFAPD-UHFFFAOYSA-N
Smiles	CC2=NC(NC(N)=N)=NC1=CC=CC=C12.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for GMQ hydrochloride

References are publications that support the biological activity of the product.

Li ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain. Mol.Pain 2010 PMID: 21143836
Alijevic and Kellenberger Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline. J.Biol.Chem. 2012 PMID: 22948146

GMQ hydrochloride

Tocris Bioscience, part of Bio-Techne | Catalog # 5028

Key Product Details

Biological Activity for GMQ hydrochloride

Technical Data for GMQ hydrochloride

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for GMQ hydrochloride

Product Documents for GMQ hydrochloride

COA

Certificate of Analysis

SDS

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