GlyH 101

Tocris Bioscience, part of Bio-Techne | Catalog # 5485

Reversible, voltage-dependent CFTR chloride channel blocker
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Key Product Details

Description

Reversible, voltage-dependent CFTR chloride channel blocker

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Product Description

GlyH 101 is a reversible, voltage-dependent CFTR chloride channel blocker (Ki = 4.3 μM). Inhibits forskolin-induced hyperpolarization in nasal potential differences and inhibits cholera toxin-induced intestinal fluid secretion in mice.

Product Specifications

Molecular Weight

493.15

Formula

C19H15Br2N3O3

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

N-2-Naphthalenyl-2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]glycine hydrazide

CAS Number

328541-79-3

PubChem ID

11260414

InChI Key

FLGYCSPPJQJZCH-LCYFTJDESA-N

SMILES

O=C(N/N=C/C3=C(O)C(Br)=C(O)C(Br)=C3)CNC2=CC1=CC=CC=C1C=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 49.31 100

Preparing Stock Solutions for GlyH 101

The following data is based on the product molecular weight 493.15

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.03 mL 10.14 mL 20.28 mL
5 mM 0.41 mL 2.03 mL 4.06 mL
10 mM 0.20 mL 1.01 mL 2.03 mL
50 mM 0.04 mL 0.20 mL 0.41 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for GlyH 101

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GlyH 101

For research use only

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