Ghrelin (human)

Name: Ghrelin (human)
Brand: Tocris Bioscience
SKU: 1463

Tocris Bioscience, part of Bio-Techne | Catalog # 1463

Citations (17)

COA / SDS

Endogenous ghrelin receptor agonist

Key Product Details

Description:	Endogenous ghrelin receptor agonist
Purity:	≥95% (HPLC)
Molecular Weight:	3370.9

View Full Technical Details for Ghrelin (human)

Technical Data
Citations

Biological Activity for Ghrelin (human)

Ghrelin (human) is an endogenous agonist peptide for the ghrelin receptor (GHS-R1a). Produced mainly by the stomach, it stimulates release of growth hormone from the pituitary gland in vitro and in vivo, and regulates feeding, growth and energy production.

Licensing Information

This peptide is distributed under license from Dr. Kangawa

Technical Data for Ghrelin (human)

M. Wt	3370.9
Formula	C₁₄₉H₂₄₉N₄₇O₄₂
Single Letter Sequence	GSSFLSPEHQRVQQRKESKKPPAKLQPR (Modifications: Ser-3 = Ser(n-octanoyl))
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	258279-04-8
PubChem ID	16133832
InChi Key	GNKDKYIHGQKHHM-RJKLHVOGSA-N
Smiles	[H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](COC(=O)CCCCCCC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ghrelin (human)

Solubility

Soluble to 2mg/ml in water

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References for Ghrelin (human)

References are publications that support the biological activity of the product.

Kojima Ghrelin is growth-hormone-releasing acylated peptide from stomach. Nature 1999 PMID: 10604470
Tolle In vivo and in vitro effects of ghrelin/motilin-related peptide on GH secretion in the rat. Neuroendocrinology 2001 PMID: 11174017
Inui Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat.Rev.Neurosci. 2001 PMID: 11483998