GC 1 New
Tocris Bioscience, part of Bio-Techne | Catalog # TB4554-RMU
GC1 synthesized to Ancillary Material Grade
Key Product Details
Description
GC1 synthesized to Ancillary Material Grade
Alternative Names
Sobetirome
Product Description
GC 1 is a thyromimetic; high affinity agonist at thyroid hormone receptor (TR) β and TRα receptors (KD values are 67 and 440 pM respectively). Displays 5- and 100-fold greater potency than the endogenous agonist T3 in vitro at TRα1 and TRβ1 receptors respectively. Promotes reverse cholesterol transport in chow- and fat-fed mice. Induces proliferation of hepatocytes and pancreatic acinar cells in rats independent of prior tissue injury.This product is Bio-Techne's ancillary Material Grade version of GC 1 (Cat. No. 4554). Suitable for use in research and further manufacturing of cell therapies. Find out more about our Ancillary Material Grade product range.
Product Specifications
Molecular Weight
328.40
Formula
C20H24O4
Storage
Store at -20°C (± 5°C)
Purity
≥98%
Chemical Name
2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid
CAS Number
211110-63-3
PubChem ID
9862248
InChI Key
QNAZTOHXCZPOSA-UHFFFAOYSA-N
SMILES
CC1=CC(OCC(O)=O)=CC(C)=C1CC2=CC(C(C)C)=C(O)C=C2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
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Product Specific Notices for GC 1
For research use only
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