Gastrin I (human)

Tocris Bioscience, part of Bio-Techne | Catalog # 3006

Selective CCK2 agonist
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Key Product Details

Description

Selective CCK2 agonist

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Product Description

Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells. Gastrin I stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively). Gastrin I is also used in the culture of stomach, intestine and pancreas organoids. For more information about using Gastrin I in the generation of gastric organoids see the Human Gastric Organoid Culture Protocol.

Product Specifications

Molecular Weight

2098.22

Formula

C97H124N20O31S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

10047-33-3

PubChem ID

16162108

InChI Key

GKDWRERMBNGKCZ-RNXBIMIWSA-N

SMILES

[H]N1[C@@H](CCC1=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in 1% Ammonia with sonication

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Background References

References are publications that support the biological activity of the product.

Product Documents for Gastrin I (human)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Gastrin I (human)

For research use only

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