Foxy 5

Tocris Bioscience, part of Bio-Techne | Catalog # 5461

Citations (3)

COA / SDS

Wnt5a peptide mimetic

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Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Wnt5a peptide mimetic

View all Other Wnt Signaling Compounds »

Product Description

Foxy 5 is a Wnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.

Product Specifications

Molecular Weight

694.77

Formula

C₂₆H₄₂N₆O₁₂S₂

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

881188-51-8

PubChem ID

44628955

InChI Key

WFZPJYYCTSHDJI-ATIWLJMLSA-N

SMILES

[H]N([C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(O)=O)C(=O)[C@H](CCSC)NC=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in PBS (pH 7.4)

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Background References

References are publications that support the biological activity of the product.

Säfholm A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells. J.Biol.Chem. 2006 PMID: 16330545
Säfholm The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin.Cancer Res. 2008 PMID: 18927296