Fluvastatin sodium

Tocris Bioscience, part of Bio-Techne | Catalog # 3309

Potent HMG-CoA reductase inhibitor
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Key Product Details

Description

Potent HMG-CoA reductase inhibitor

View all HMG-CoA Reductase Inhibitors »

Product Description

Fluvastatin sodium is an orally active, potent and competitive HMG-CoA reductase inhibitor (IC50 = 40 -100 nM at human liver microsomes). Inhibits vascular smooth muscle proliferation in vitro (IC50 = 70 nM) and exhibits antihypercholesterolemic and antioxidant activity in vivo.

Product Specifications

Molecular Weight

433.45

Formula

C24H25FNNaO4

Storage

Desiccate at -20°C

Purity

≥98% (HPLC)

Chemical Name

(±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt

CAS Number

93957-55-2

PubChem ID

76969265

InChI Key

BNZHURJBOKXWJX-ZKBIPVLYSA-L

SMILES

[Na+].[Na+].CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC([O-])=O)=C(C2=CC=C(F)C=C2)C2=C1C=CC=C2.CC(C)N1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(C2=CC=C(F)C=C2)C2=C1C=CC=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 10.84 25
DMSO 43.34 100

Preparing Stock Solutions for Fluvastatin sodium

The following data is based on the product molecular weight 433.45

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.31 mL 11.54 mL 23.07 mL
5 mM 0.46 mL 2.31 mL 4.61 mL
10 mM 0.23 mL 1.15 mL 2.31 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Fluvastatin sodium

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Fluvastatin sodium

For research use only

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