Flupenthixol dihydrochloride
Tocris Bioscience, part of Bio-Techne | Catalog # 4057
Dopamine antagonist
Key Product Details
Description
Dopamine antagonist
Alternative Names
Flupentixol
Product Description
Flupenthixol dihydrochloride is an antipsychotic drug. Exhibits antagonistic activity at dopamine D1-5 receptors. Used in schizophrenia treatment.This compound is a mixture of E/Z isomers (ratio: 60:40).
Product Specifications
Molecular Weight
507.44
Formula
C23H25F3N2OS.2HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
CAS Number
2413-38-9
PubChem ID
17011
InChI Key
IOVDQEIIMOZNNA-UHFFFAOYSA-N
SMILES
Cl.Cl.OCCN1CCN(CCC=C2C3=CC(=CC=C3SC3=C2C=CC=C3)C(F)(F)F)CC1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 50.74 | 100 | |
| DMSO | 25.37 | 50 |
Preparing Stock Solutions
for Flupenthixol dihydrochloride
The following data is based on the product molecular weight 507.44
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.97 mL | 9.85 mL | 19.71 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
| 10 mM | 0.20 mL | 0.99 mL | 1.97 mL |
| 50 mM | 0.04 mL | 0.20 mL | 0.39 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Peuch Pharmacological properties of new antipsychotic agents: Use of animal models. Neuropharmacology 1981 PMID: 6119637
Product Specific Notices for Flupenthixol dihydrochloride
For research use only
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