Purine analog; inhibits DNA synthesis
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Key Product Details
Description: | Purine analog; inhibits DNA synthesis |
Chemical Name: | 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 285.23 |
Citations for Fludarabine (10)
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Citations are publications that use Bio-Techne products. Selected citations for Fludarabine include:
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Yuwei et al.
(2023)
Age-dependent Pdgfrβ signaling drives adipocyte progenitor dysfunction to alter the beige adipogenic niche in male mice.
Nat Commun.
14:1806
PMID: 37002214 -
Xiang et al.
(2022)
A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression.
J Exp Clin Cancer Res.
41:174
PMID: 35562774 -
Alexey et al.
(2022)
Attenuation of SARS-CoV-2 replication and associated inflammation by concomitant targeting of viral and host cap 2'-O-ribose methyltransferases.
EMBO J.
41:e111608
PMID: 35833542 -
Brij B et al.
(2021)
Resolving macrophage polarization through distinct Ca2+ entry channel that maintains intracellular signaling and mitochondrial bioenergetics.
iScience.
24:103339
PMID: 34816101 -
Fred et al.
(2020)
STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina.
Cell Rep.
30:2195-2208.e5
PMID: 32075759 -
Beate et al.
(2020)
Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin.
Cell Mol Immunol.
17:380-394
PMID: 31324882 -
Haiyan et al.
(2019)
E3-ubiquitin ligase TRIM6 aggravates myocardial ischemia/reperfusion injury via promoting STAT1-dependent cardiomyocyte apoptosis.
Aging (Albany NY).
11:3536-3550
PMID: 31171760 -
Odendall et al.
(2014)
Diverse intracellular pathogens activate type III IF. expression from peroxisomes.
Nat Immunol.
15:717
PMID: 24952503 -
Nathalie et al.
(2014)
Fludarabine downregulates indoleamine 2,3-dioxygenase in tumors via a proteasome-mediated degradation mechanism.
PLoS One.
9:e99211
PMID: 24911872 -
Robinson et al.
(2013)
RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs.
PLoS One.
8:e78641
PMID: 24265703
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Species: MouseAssay Type: In VitroCell Line/Tissue: Hepatic stellate cells and hepatocytesI used it to check its effect on drug stimulated hepatic stellate cell and its signaling.
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