FH 535

Tocris Bioscience, part of Bio-Techne | Catalog # 4344

Inhibitor of Wnt/β-catenin signaling
Discontinued Product
4344 has been discontinued. View all beta-Catenin Inhibitors products.

Key Product Details

Description

Inhibitor of Wnt/β-catenin signaling

View all beta-Catenin Inhibitors »

Product Description

FH 535 is an inhibitor of Wnt/β-catenin signaling and dual antagonist of PPARγ/δ activity. Suppresses β-catenin/Tcf-mediated transcription; inhibits β-catenin and GRIP1 recruitment to PPARγ and δ. Exhibits antiproliferative effects in transformed colon, lung and liver cancer cell lines.

Product Specifications

Molecular Weight

361.20

Formula

C13H10Cl2N2O4S

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide

CAS Number

108409-83-2

PubChem ID

3463933

InChI Key

AXNUEXXEQGQWPA-UHFFFAOYSA-N

SMILES

ClC1=CC(S(NC2=C(C)C=C([N+]([O-])=O)C=C2)(=O)=O)=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.09 75

Preparing Stock Solutions for FH 535

The following data is based on the product molecular weight 361.20

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 3.69 mL 18.46 mL 36.91 mL
3.75 mM 0.74 mL 3.69 mL 7.38 mL
7.5 mM 0.37 mL 1.85 mL 3.69 mL
37.5 mM 0.07 mL 0.37 mL 0.74 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for FH 535

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for FH 535

For research use only

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