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Febuxostat

Tocris Bioscience, part of Bio-Techne | Catalog # 4427

Xanthine oxidase inhibitor
Catalog #
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4427/10
4427/50

Key Product Details

Description

Xanthine oxidase inhibitor

Alternative Names

TEI 6720,TMX 67

Product Description

Febuxostat is a non-purine inhibitor of xanthine oxidase (Ki = 1.2 nM). Binds to a channel leading to the enzyme active site; obstructs substrate binding.

Product Specifications

Molecular Weight

316.37

Formula

C16H16N2O3S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid

CAS Number

144060-53-7

PubChem ID

134018

InChI Key

BQSJTQLCZDPROO-UHFFFAOYSA-N

SMILES

CC1=C(C(O)=O)SC(C2=CC(C#N)=C(OCC(C)C)C=C2)=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 23.73 75
Ethanol 15.82 50

Preparing Stock Solutions for Febuxostat

The following data is based on the product molecular weight 316.37

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 4.21 mL 21.07 mL 42.14 mL
3.75 mM 0.84 mL 4.21 mL 8.43 mL
7.5 mM 0.42 mL 2.11 mL 4.21 mL
37.5 mM 0.08 mL 0.42 mL 0.84 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Product Documents for Febuxostat

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Febuxostat

For research use only

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