Exo1

Name: Exo1
Brand: Tocris Bioscience
SKU: 1850

Tocris Bioscience, part of Bio-Techne | Catalog # 1850

Citations (16)

COA / SDS

Inhibits Golgi-ER traffic; blocks exocytosis

Discontinued Product

1850 has been discontinued. View all Translocation, Exo/Endocytosis Products products.

Key Product Details

Description:	Inhibits Golgi-ER traffic; blocks exocytosis
Chemical Name:	2-[(4-Fluorobenzoyl)amino]-benzoic acid methyl ester
Purity:	≥99% (HPLC)
Molecular Weight:	273.26

View Full Technical Details for Exo1

Technical Data
Citations

Biological Activity for Exo1

Exo1 is a reversible inhibitor of vesicular trafficking between endoplasmic reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1 GTPase activity and inhibits exocytosis (IC₅₀ ~ 20 μM). Has similar, but not identical, action to brefeldin A (Cat. No. 1231).

Technical Data for Exo1

M. Wt	273.26
Formula	C₁₅H₁₂FNO₃
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	461681-88-9
PubChem ID	310557
InChi Key	KIAPWMKFHIKQOZ-UHFFFAOYSA-N
Smiles	COC(=O)C1=CC=CC=C1NC(=O)C1=CC=C(F)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for Exo1

References are publications that support the biological activity of the product.

Feng Exo1: A new chemical inhibitor of the exocytic pathway. Proc.Natl.Acad.Sci.U.S.A. 2003 PMID: 12738886

Exo1

Tocris Bioscience, part of Bio-Techne | Catalog # 1850

Key Product Details

Biological Activity for Exo1

Technical Data for Exo1

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Exo1

Product Documents for Exo1

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

保持关注