Ethyl LipotF

Tocris Bioscience, part of Bio-Techne | Catalog # 5950

Selective FTO inhibitor
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Key Product Details

Description

Selective FTO inhibitor

View all Other Oxidase/Oxygenase Compounds »

Product Description

Ethyl LipotF is a selective FTO inhibitor (IC50 = 0.81 μM). Exhibits >30-fold selectivity for FTO over ALKBH2, 3 and 5 and >100-fold selectivity over PHD2 and JMJD2A. Increases levels of modified N6-methyladenosine (m6A) in HeLa cells in a concentration-dependent manner.

Product Specifications

Molecular Weight

353.38

Formula

C19H19N3O4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

Ethyl (E)-4-(2-(4-benzylnicotinoyl)hydrazinyl)-4-oxobut-2-enoate

CAS Number

1808089-27-1

InChI Key

XUKLGMSFWAEOPR-CMDGGOBGSA-N

SMILES

O=C(NNC(/C=C/C(OCC)=O)=O)C1=C(CC2=CC=CC=C2)C=CN=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 35.34 100
Ethanol 7.07 20

Preparing Stock Solutions for Ethyl LipotF

The following data is based on the product molecular weight 353.38

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.83 mL 14.15 mL 28.30 mL
5 mM 0.57 mL 2.83 mL 5.66 mL
10 mM 0.28 mL 1.41 mL 2.83 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ethyl LipotF

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ethyl LipotF

For research use only

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