EML 425
Tocris Bioscience, part of Bio-Techne | Catalog # 5646
Reversible and non-competitive CBP/p300 inhibitor
Key Product Details
Description
Reversible and non-competitive CBP/p300 inhibitor
Product Description
EML 425 is a reversible and non-competitive CBP/p300 inhibitor (IC50 values are 1.1 and 2.9 μM, respectively). Cell permeable.Product Specifications
Molecular Weight
440.49
Formula
C27H24N2O4
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
5-[(4-Hydroxy-2,6-dimethylphenyl)methylene]-1,3-bis(phenylmethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
CAS Number
1675821-32-5
PubChem ID
91826273
InChI Key
LUGQBJDYUPNAQQ-UHFFFAOYSA-N
SMILES
CC1=C(/C=C2C(N(CC3=CC=CC=C3)C(N(CC4=CC=CC=C4)C\2=O)=O)=O)C(C)=CC(O)=C1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 44.05 | 100 |
Preparing Stock Solutions
for EML 425
The following data is based on the product molecular weight 440.49
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.27 mL | 11.35 mL | 22.70 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.54 mL |
| 10 mM | 0.23 mL | 1.14 mL | 2.27 mL |
| 50 mM | 0.05 mL | 0.23 mL | 0.45 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
Product Specific Notices for EML 425
For research use only
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