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DuP 697

Tocris Bioscience, part of Bio-Techne | Catalog # 1430

Cyclooxygenase-2 (COX-2) inhibitor
Discontinued Product
1430 has been discontinued. View all Cyclooxygenase Inhibitors products.

Key Product Details

Description

Cyclooxygenase-2 (COX-2) inhibitor

Product Description

DuP 697 is a potent and selective inhibitor of cyclooxygenase-2 (IC50 values are 10 and 800 nM for COX-2 and COX-1 respectively). Inhibits prostaglandin synthesis and is anti-inflammatory in vivo. Orally active.

Product Specifications

Molecular Weight

411.30

Formula

C17H12BrFO2S2

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-thiophene

CAS Number

88149-94-4

PubChem ID

3177

InChI Key

AJFTZWGGHJXZOB-UHFFFAOYSA-N

SMILES

CS(=O)(=O)C1=CC=C(C=C1)C1=C(SC(Br)=C1)C1=CC=C(F)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 41.13 100

Preparing Stock Solutions for DuP 697

The following data is based on the product molecular weight 411.30

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.43 mL 12.16 mL 24.31 mL
5 mM 0.49 mL 2.43 mL 4.86 mL
10 mM 0.24 mL 1.22 mL 2.43 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

Molarity Calculator

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Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for DuP 697

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DuP 697

For research use only

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