DOPE

Tocris Bioscience, part of Bio-Techne | Catalog # 7175

Liposome/lipoplex transfection enhancer
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Key Product Details

Description

Liposome/lipoplex transfection enhancer

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Product Description

DOPE is a liposome/lipoplex transfection reagent. Enhances liposome and lipoplex transfection efficiency in combination with DA, DOTAP or DC-cholesterol (Cat. No. 7176).

Please note: exact ratio for use and transfection efficiency is dependent on cell line used.

Product Specifications

Molecular Weight

744.05

Formula

C41H78NO8P

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(9Z)-1,1'-[(1R)-1-[[[(2-Aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] 9-octadecenoic acid ester

CAS Number

4004-05-1

PubChem ID

9546757

InChI Key

MWRBNPKJOOWZPW-NYVOMTAGSA-N

SMILES

CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](CO[P](O)(=O)OCCN)OC(=O)CCCCCCC\C=C/CCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
chloroform 74.4 100

Preparing Stock Solutions for DOPE

The following data is based on the product molecular weight 744.05

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.34 mL 6.72 mL 13.44 mL
5 mM 0.27 mL 1.34 mL 2.69 mL
10 mM 0.13 mL 0.67 mL 1.34 mL
50 mM 0.03 mL 0.13 mL 0.27 mL

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product.

Product Documents for DOPE

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DOPE

For research use only

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