Selective sigma (σ) agonist (σ1> σ2)
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Key Product Details
Description: | Selective sigma (σ) agonist (σ1> σ2) |
Chemical Name: | (1R,2S)-rel-2-[(4-Hydroxy-4-phenyl-1-piperidinyl)methyl]-1-(4-methylphenyl)-cyclopropanecarboxylic acid methyl ester oxalate |
Purity: | ≥99% (HPLC) |
Molecular Weight: | 469.53 |
Citations for (±)-PPCC oxalate (6)
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Citations are publications that use Bio-Techne products. Selected citations for (±)-PPCC oxalate include:
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María et al.
(2022)
αN-Acetyl β-Endorphin Is an Endogenous Ligand of ς1Rs That Regulates Mu-Opioid Receptor Signaling by Exchanging G Proteins for ς2Rs in ς1R Oligomers.
Int J Mol Sci.
24
PMID: 36614024 -
María et al.
(2020)
The ALS-related ς1R E102Q Mutant Eludes Ligand Control and Exhibits Anomalous Response to Calcium.
Int J Mol Sci.
21
PMID: 33020464 -
Rodríguez-Muñoz et al.
(2018)
Fenfluramine diminishes NMDA receptor-mediated seizures via its mixed activity at serotonin 5HT2A and type 1 sigma receptors.
Oncotarget.
9:23373
PMID: 29805740 -
Rodríguez-Muñoz et al.
(2018)
Cannabidiol enhances MOR antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor.
Mol Brain.
11:51
PMID: 30223868 -
Sánchez-Blázquez et al.
(2018)
Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice.
Int J Neuropsychopharmacol.
21:938
PMID: 29860313 -
Malik et al.
(2015)
The effects of σ (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice.
J Biol Chem.
172:2519
PMID: 25573298
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