DIM-C-pPhOH

Tocris Bioscience, part of Bio-Techne | Catalog # 6377

Nur77 antagonist
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Key Product Details

Description

Nur77 antagonist

View all Nuclear Hormone Receptor 4A Antagonists »

Product Description

DIM-C-pPhOH is a Nur77 (NR4A1) antagonist. Inhibits TGF-β induced cell migration of breast cancer cell lines. Promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines. Mimics effects of Nur77 RNAi silencing.

Product Specifications

Molecular Weight

338.408

Formula

C23H18N2O

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

1,1-Bis(3'-indolyl)-1-(p-hydroxyphenyl)methane

CAS Number

151358-47-3

PubChem ID

2940609

InChI Key

QCPDFNWJBQMXLI-UHFFFAOYSA-N

SMILES

OC1=CC=C(C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 33.84 100
Ethanol 33.84 100

Preparing Stock Solutions for DIM-C-pPhOH

The following data is based on the product molecular weight 338.408

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.96 mL 14.78 mL 29.55 mL
5 mM 0.59 mL 2.96 mL 5.91 mL
10 mM 0.30 mL 1.48 mL 2.96 mL
50 mM 0.06 mL 0.30 mL 0.59 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for DIM-C-pPhOH

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DIM-C-pPhOH

For research use only

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