Devazepide

Tocris Bioscience, part of Bio-Techne | Catalog # 2304

Selective, orally active CCK1 receptor antagonist
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Key Product Details

Description

Selective, orally active CCK1 receptor antagonist

Alternative Names

L-364,718,MK 329

View all CCK1 Receptor Antagonists »

Product Description

Devazepide is a potent, orally active CCK1 (CCK-A) receptor antagonist that displays appetite-stimulant effects. Blocks the anorectic response to CCK-8 and increases food intake in rats following systemic and i.c.v administration.

Product Specifications

Molecular Weight

408.46

Formula

C25H20N4O2

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

N-[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide

CAS Number

103420-77-5

PubChem ID

443375

InChI Key

NFHRQQKPEBFUJK-HSZRJFAPSA-N

SMILES

CN1C2=CC=CC=C2C(=N[C@H](NC(=O)C2=CC3=C(N2)C=CC=C3)C1=O)C1=CC=CC=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.85 100
Ethanol 20.42 50

Preparing Stock Solutions for Devazepide

The following data is based on the product molecular weight 408.46

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.45 mL 12.24 mL 24.48 mL
5 mM 0.49 mL 2.45 mL 4.90 mL
10 mM 0.24 mL 1.22 mL 2.45 mL
50 mM 0.05 mL 0.24 mL 0.49 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Devazepide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Devazepide

For research use only

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