[D-Trp7,9,10]-Substance P
Tocris Bioscience, part of Bio-Techne | Catalog # 1884
Inhibits M1 ACh receptor activation of Gq/11
Discontinued Product
1884 has been discontinued.
View all G Protein (Heterotrimeric) Inhibitors products.
Key Product Details
Description
Inhibits M1 ACh receptor activation of Gq/11
Alternative Names
GPAnt-2 analog
Product Description
[D-Trp7,9,10]-Substance P is a substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.Product Specifications
Molecular Weight
1588.89
Formula
C79H105N21O13S
Storage
Store at -20°C
CAS Number
89430-38-6
PubChem ID
16143852
InChI Key
ZDXXOQXJCDHSRG-GGDSLUOHSA-N
SMILES
[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
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Background References
References are publications that support the biological activity of the product.
- Mukai G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding. J.Biol.Chem. 1992 PMID: 1379592
Product Specific Notices for [D-Trp7,9,10]-Substance P
For research use only
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