D-Amphetamine sulfate
Tocris Bioscience, part of Bio-Techne | Catalog # 2813
Induces dopamine, 5-HT and noradrenalin release; also α7 nAChR antagonist
Key Product Details
Description
Induces dopamine, 5-HT and noradrenalin release; also α7 nAChR antagonist
Alternative Names
Dextroamphetamine sulfate
Product Description
D-Amphetamine sulfate is a cNS stimulant. Targets monoamine transporters to elevate synaptic levels of noradrenalin, dopamine and serotonin. Also α7 nAChR antagonist .Product Specifications
Molecular Weight
184.25
Formula
C9H13N.1/2H2SO4
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
(+)-α-Methylphenethylamine hemisulfate salt
CAS Number
51-63-8
PubChem ID
5825
InChI Key
PYHRZPFZZDCOPH-QXGOIDDHSA-N
SMILES
N[C@@H](C)CC1=CC=CC=C1.N[C@@H](C)CC2=CC=CC=C2.OS(O)(=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 18.43 | 100 |
Preparing Stock Solutions
for D-Amphetamine sulfate
The following data is based on the product molecular weight 184.25
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.43 mL | 27.14 mL | 54.27 mL |
| 5 mM | 1.09 mL | 5.43 mL | 10.85 mL |
| 10 mM | 0.54 mL | 2.71 mL | 5.43 mL |
| 50 mM | 0.11 mL | 0.54 mL | 1.09 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Garton Amphetamine enantiomers inhibit homomeric a7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans. Neuropharmacology 2018 PMID: 30359640
- Cartmell The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-Amphetamine motor behaviors in rats. J.Pharmacol.Exp.Ther. 1999 PMID: 10490900
- Rothman and Baumann Balance between DA and serotonin release modulates behavioral effects of Amphetamine-type drugs. Ann.N.Y.Acad.Sci. 2006 PMID: 17105921
- Barr Effects of withdrawal from an escalating dose schedule of d-Amphetamine on sexual behavior in the male rat. Pharmacol.Biochem.Behav. 1999 PMID: 10548277
Product Specific Notices for D-Amphetamine sulfate
For research use only
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